Chemical Constituents and Biological Activities of Glycosmis Chlorosperma Var. Elmeri (Merr.) Stone (Rutaceae)

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Published: Apr 27, 2006

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Rosmiati Abdullah
Mawardi Rahmani
Abdul Manaf Ali
Hazar Bebe Mohd Ismail
Mohd Aspollah Sukari
Ee G.C.L
ulius Kulip

Abstract

Detailed investigation on the leaves and barks of Glycosmis chlorosperma has led to the isolation and identification of a chalcone, dihydroglychalcone (1) and three sulphones - dambullin (2), sakambullin (3) and methylgerambullin (4), along with the common triterpene, stigmasterol. Compounds (1) (2) and (3) showed cytotoxic activity towards CEM-SS T-lymphoblastic cell lines. However, only dambullin (2) showed activity against pathogenic bacteria and fungi. We wish to report the isolation and bioassay results of the crude extracts and pure compounds.

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How to Cite
Abdullah, R., Rahmani, M., Manaf Ali, A., Mohd Ismail, H. B., Sukari, M. A., G.C.L, E., & Kulip, ulius. (2006). Chemical Constituents and Biological Activities of Glycosmis Chlorosperma Var. Elmeri (Merr.) Stone (Rutaceae). Malaysian Journal of Science, 25(1), 45–51. Retrieved from http://mjs.um.edu.my/index.php/MJS/article/view/8178
Issue
Vol. 25 No. 1 (2006)
Section
Original Articles

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